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RESEARCH

My laboratory applies a wide variety of in vitro (eg microcalorimetry, light scattering and optical spectroscopy) in combination with in silico (eg molecular modeling, molecular dynamics and virtual screening) biophysical methods to study the basic mechanisms driving protein-ligand interactions in the context of cellular processes pertinent to human health and disease.

A key emphasis of my laboratory is to exploit fundamental principles emerging from our basic research toward the rational design of novel therapeutic approaches harboring greater efficacy coupled with low toxicity for the treatment of human disease.

Importantly, in the wake of ever rising costs coupled with lengthy clinical trials associated with de novo drug design, we have recently also begun to devote a substantial part of our efforts toward repurposing old or existing drugs for new indications for which no other therapeutic alternatives are available on the basis of structure-based rational approach.



BIOGRAPHY


Born in rural Kashmir in 1971, Amjad's early life set the tone for what would turn out to be an example of what can be achieved in life. With no tellies or tubbies, his childhood centered upon herding goats, riding donkeys and the crushing marks of thorns on the soles of his feet bear testament to the hard work ethic that embodies his soul. In 1985, at the tender age of thirteen, the opportunity to relocate to England offered Amjad a new lease of life.

Equipped with only a handful of words of the host language coupled with a setting that could not have been more alien to that of his upbringing in his native Kashmir, England presented Amjad with nothing short of a culture shock. Yet, Amjad would rise to the challenge against all odds—a feature that would become the epitomy of his later life. Although he faced many hurdles early on in his new hunting ground, it was not long before Amjad discovered that his passion lay in science and that scientific curiosities challenged his innermost conscience. Despite the family pressure to pursue medicine, he began to specialize in science from around mid teenage and through his hard work, dedication and stamina combined with an-equal-opportunity land, Amjad rose through the academic ranks quickly and with flying colors.

Although a physics whiz, Amjad's interest in understanding the intricacies of life meant that he had to settle for an undergraduate degree in a biomedical science. In 1994, he obtained his baccalaureate with First Class Honors (Summa Cum Laude) in Biochemistry from the University of Manchester in the north of England. Amjad's doctoral research focussed on elucidating the biophysical principles underlying the folding of proteins within biological membranes. After obtaining his doctorate from the University of London in 1998, Amjad joined Dr Ming-Ming Zhou's laboratory at the Icahn School of Medicine—with a highly competitive postdoctoral fellowship, courtesy of Wellcome Trust of the United Kingdom. Amjad's charming and gregarious personality combined with his passion for science soon struck a chord with Dr Zhou and the scientific partnership would last for the next six years. During his postdoctoral training with Dr Zhou, Amjad not only mastered the art of structural biology but also (co-)authored nearly two dozen papers in high-profile scientific journals.

In 2004, Amjad's excellent scientific productivity and promise as an independent scholar led to his recruitment at the tenure-track rank of Assistant Professor at the Leonard Miller School of Medicine of the University of Miami. His continuing high scientific productivity was rewarded with a promotion to the rank of Associate Professor in 2010. In 2012, he became a tenured faculty. Voila!




AMJAD FAROOQ PhD DIC
Associate Professor
Dept of Biochemistry
Miller School of Medicine
University of Miami
Miami, FL 33136

Location
Gautier Bldg #116
Medical Campus

Street Address
1011 NW 15 ST #116
Miami, FL 33136

Direct Contact
Call @ 305-243-2429
Fax @ 305-243-3955
amjad@farooqlab.net


Professional Links
  • PubMed Papers
  • Book Chapters
  • PhD Thesis
  • PhD Defense
  • PhD Diploma
  • DIC Diploma
  • BSc Diploma


  • PROFILE
    Alma
    Maters
    Imperial College London (DIC 1998)
    University of London (PhD 1998)
    University of Manchester (BSc 1994)
    Bradford College (ALs 1991)
    Academic
    Appointments
    Associate Professor, University of Miami (2010-date)
    Assistant Professor, University of Miami (2004-2010)
    Research Instructor, Icahn School of Medicine (2002-2004)
    Postdoc Trainee, Icahn School of Medicine (1998-2002)
    Research
    Interests
    - Computational Biology
    - Structural Biochemistry
    - Molecular Biophysics
    - Cellular Signaling
    - Drug Discovery
    Scientific
    Expertise
    - Protein Structure (NMR | MM | MD)
    - Protein Hydrodynamics (SLS | DLS | ALS)
    - Protein Thermodynamics (ITC | DSC | PPC)
    - Protein Folding (SF | FS | CD | UVV)
    - Drug Design (LD | VS | RS)
    Linux
    Prowess
    - Programming Languages (CSH | TCL | Python | Perl)
    - System Administration (NFS | Samba | RAID | SELinux)
    - Super Computing (SSI | MPI | PBS)
    - Web Development (HTML | JS | PHP | SQL)
    - Apache Server (CGI | ModSecurity | AutoShutdown)
    Major
    Funding
    Sylvester Comprehensive Cancer Center (2004-date)
    National Institutes of Health (2008-2014)
    American Heart Association (2006-2009)
    Born 1971 @ Mirpur, Kashmir
    Nationality Pak-British-American (triple-citizen)
    Nomadic
    History
    Miami, Florida (2004-date)
    Manhattan, New York (1998-2004)
    London, England (1995-1998)
    Oxford, England (1994-1995)
    Manchester, England (1991-1994)
    Bradford, England (1985-1991)
    Mirpur, Kashmir (1971-1985)
    Lingual
    Capability
    - Scholarly in English
    - Literary in Urindi
    - Native in Punjabi
    - Proficient in Spanish
    - Basic French
    - Little Arabic


    Copyright © 2004 Farooq Laboratory